# Mendelian Genetics Problems - Advanced (Grades 11-12)

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## Mendelian Genetics Problems - Advanced

1.

A man has six fingers on each hand and six toes on each foot. His wife and their sons have the normal number of digits. If extra digits is a dominant trait, what percentage of the children would be expected to have the extra fingers and toes?

- 1/2
- 1/3
- 1/4
- 3/4

2.

A worm has a genotype of AaBbCcDd. Based upon this information, what are the possible genotypes of the parents?

- AABBccDD and aabbccdd
- AABBCCDD and aabbccdd
- aaBbCcDd and aaBbCcDd
- AabbCCDd and Aabbccdd

3.

Phenylketonuria (PKU) is an inherited disease that is recessive in origin. If a couple, who are both carriers, have three children, what is the probability that all three children are of normal phenotype?

- 3/64
- 5/64
- 18/64
- 27/64

4.

If two parents both are carriers for phenylketonuria, what is the probability that one of their three children will have the disease?

- 3/64
- 27/64
- 37/64
- 16/64

5.

In corn plants, having kernel color (c) is recessive to the gene that inhibits kernel color (C). Color appears when the homozygous condition is present. At a different locus, the dominant allele (P) results in purple kernels, whereas the recessive allele (p) results in red kernels, again when homozygous. If plants heterozygous for both loci are crossed, what will be the phenotypic ratio of the offspring?

- 4 colorless : 10 purple : 2 red
- 12 colorless : 3 purple : 1 red
- 2 colorless : 2 purple : 12 red
- 9 colorless : 5 purple : 2 red

6.

Tigers have a recessive allele that causes both a cross-eyed condition and an absence of pigmentation in their fur (resulting in white tigers). If two normal-appearing tigers that are heterozygous for both traits are mated, what percentage of the cross-eyed offspring would be white?

- 100%
- 25%
- 50%
- 75%

7.

Hank and Marci each have a sister who expresses sickle cell anemia. Neither Hank nor Marci nor any of their parents have the disease, and none of them have been tested to determine if they are carriers. What is the probability that a child of Hank and Marci will have sickle cell anemia?

- 1/8
- 1/9
- 1/3
- 1/2

8.

A man with type A blood has a child with a woman who has type B blood. The child has type O blood. What can be determined about the blood types of any future children this couple may have?

- All future children will also have type O blood.
- There is a 10% chance that future children will be type AB.
- The future children have an equal chance of having all of the four possible blood types.
- The only other blood type that is possible for the future children to have is type B.

9.

One characteristic Mendel examined was pea pod shape. If a pea plant that is heterozygous for inflated pods (Ii) is crossed with one that is homozygous for constricted pods (ii), what are the possible genotypic and phenotypic ratios of the offspring?

- The genotypic ratio would be 1 Ii : 1 ii. The phenotypic ratio would be 1 inflated : 1 constricted.
- The genotypic ratio would be 1 II : 1 Ii : 2 ii. The phenotypic ratio would be 2 inflated : 2 constricted.
- The genotypic ratio would be 3 Ii : 1 Ii. The phenotypic ratio would be 4 constricted : 0 inflated.
- The genotypic ratio would be 1 II : 2 Ii : 1 ii. The phenotypic ratio would be 2 inflated : 2 constricted.

10.

A cat has been found that possesses curled ears. Many people find this trait favorable and would like to incorporate the allele for this trait into the cat population. If you are the owner of the mutant cat, how would you determine whether the trait is dominant or recessive in order to pass the trait onto the cat's offspring?

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