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Mendelian Genetics Problems - Advanced (Grades 11-12)

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Mendelian Genetics Problems - Advanced

A man has six fingers on each hand and six toes on each foot. His wife and their sons have the normal number of digits. If extra digits is a dominant trait, what percentage of the children would be expected to have the extra fingers and toes?
  1. 1/2
  2. 1/3
  3. 1/4
  4. 3/4
A species of worm has a genotype of AaBbCcDd. Based upon this information, what is the possible genotype of each parent?
  1. AABBccDD and aabbccdd
  2. AABBCCDD and aabbccdd
  3. aaBbCcDd and aaBbCcDd
  4. AabbCCDd and Aabbccdd
Phenylketonuria (PKU) is an inherited disease that is recessive in origin. If a couple, who are both carriers, have three children, what is the probability that all three children are of normal phenotype?
Table 2x2
  1. 3/64
  2. 5/64
  3. 18/64
  4. 27/64
If two parents both are carriers for phenylketonuria, what is the probability that one of their three children will have the disease?
Table 2x2
  1. 3/64
  2. 27/64
  3. 37/64
  4. 16/64
In corn plants, having kernel color (c) is recessive to the gene that inhibits kernel color (C). The color appears when the homozygous condition is present. At a different locus, the dominant allele (P) turns the kernels purple, while the recessive allele (p) causes different colors, again when homozygous. If plants are heterozygous for both loci are crossed, what will be the phenotypic ratio of the offspring?
Table 4x4
  1. 4 colorless : 10 purple : 2 red
  2. 12 colorless: 3 purple : 1 red
  3. 2 colorless : 2 purple : 12 red
  4. 9 colorless : 5 purple : 2 red
Tigers have a recessive allele that causes both a cross-eyed condition and an absence of pigmentation in their fur (white tigers). If two normal-appearing tigers that are heterozygous for both traits are mated, what percentage of the cross-eyed offspring would be white?
Table 4x4
  1. 100%
  2. 25%
  3. 50%
  4. 75%
Hank and Marci each have a sister who expresses sickle-cell anemia. Neither Hank nor Marci nor any of their parents have the disease and none of them have been tested to see if they are carriers. What is the probability that a child of Hank and Marci will have sickle-cell anemia?
Table 2x2
  1. 1/8
  2. 1/9
  3. 1/3
  4. 1/2
A man with type A blood has a child with a woman who has type B blood. The child has type O blood. What can be determined about the blood types of any future children this couple may have?
  1. All future children will also have type O blood.
  2. There is a 10% chance that most future children will be type AB.
  3. The future children have an equal chance of having all of the four possible blood types.
  4. The only other blood type that is possible for the future children to have is type B.
One characteristic Mendel examined was pea pod shape. If a pea plant that is heterozygous for inflated pots (Ii) is crossed with one that is homozygous for constricted pods (ii), what are the possible genotypic and phenotypic ratios of the offspring?
Table 2x2
  1. The genotypic ratio would be 1 Ii : 1 ii. The phenotypic ratio would be 1 inflated: 1 constricted.
  2. The genotypic ratio would be 1 II : 1 Ii : 2 ii. The phenotypic ratio would be 2 inflated: 2 constricted.
  3. The genotypic ratio would be 3 Ii : 1 Ii. The phenotypic ratio would be 4 constricted: 0 inflated.
  4. The genotypic ratio would be 1 II : 2 Ii : 1 ii. The phenotypic ratio would be 2 inflated: 2 constricted.
A cat has been found that possess curled ears. Many people find this trait favorable and are trying to incorporate the allele for this trait into the cat population. Over time, hundred of offspring have been born that possess this trait. If you were this cat's original owner, how would you determine if this trait were dominant or recessive in order to pass the trait onto the cat's offspring?

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